“Next target is cancer”

(AP) “The scientist who won the race to deliver the first widely used coronavirus vaccine says people can rest assured the shots are safe, and the technology behind it will soon be used to fight another global scourge — cancer.

The vaccines made by BioNTech-Pfizer and U.S. rival Moderna uses messenger RNA, or mRNA, to carry instructions into the human body for making proteins that prime it to attack a specific virus. The same principle can be applied to get the immune system to take on tumors.

“We have several different cancer vaccines based on mRNA,” said Tureci, who is BioNTech’s chief medical officer.

Asked when such a therapy might be available, Tureci said “that’s very difficult to predict in innovative development. But we expect that within only a couple of years, we will also have our vaccines (against) cancer at a place where we can offer them to people.

Before you say, impossible, consider that the best scientific minds in the world were certain it was impossible to create a COVID-19 vaccine in less than a year.

Ping Pong


Yesterday I played ping pong with my friend John for the first time in more than a year. Before the pandemic we’d get together every couple of weeks in his basement. John is good enough to call it table tennis but it will always be ping pong for me.

We chat as we play and boy was I ready to interact with another human. John and his wife, Peggy, have both been vaccinated for COVID (as have I) so we felt safe as we played and talked. It will be a while (never?) before I take such simple pleasure for granted.

Buddha Trump

A cast of “Trump, the Buddha of Knowing of the Western Paradise,” by the Chinese sculptor Hong Jinshi.
“A furniture maker and decorator in China created a stir — and inspired copycats — by casting a ceramic sculpture of the former president in a meditative pose that evokes the Buddha. Mr. Hong’s sculpture reflects an abiding cultural fascination with Mr. Trump in China that began with his election. Many admired his brash style, his family’s business ties to China and even his early courtship of China’s leader, Xi Jinping, whom he called “an incredible guy.” (New York Times)

Forgetting how to be normal

“We’re all walking around with some mild cognitive impairment,” said Mike Yassa, a neuroscientist at UC Irvine. “Based on everything we know about the brain, two of the things that are really good for it are physical activity and novelty. A thing that’s very bad for it is chronic and perpetual stress.” Living through a pandemic—even for those who are doing so in relative comfort—“is exposing people to microdoses of unpredictable stress all the time,” said Franklin, whose research has shown that stress changes the brain regions that control executive function, learning, and memory.

Late-Stage Pandemic Is Messing With Your Brain

Wallets, billfolds and money-clips

When the nurse handed me my vaccination card she said, “Keep this in your wallet.” Hmm, where did I put my wallet? For the past year we’ve been paying for stuff online with a credit card.

I found my wallet and decided to do a little house cleaning. How much of this stuff do I really need to have with me every time I leave the house? I can pay for gas and groceries using my phone and ApplePay. And I’ve always kept some cash in a money clip. I see that some get by with their driver’s license and a credit/debit card in a phone case. Which got me wondering… do young folks still carry wallets?

“The difference between billfold and wallet is that a billfold is a small, folding sleeve or case designed to hold paper currency, as well as credit cards, pictures, etc while wallet is a small case, often flat and often made of leather, for keeping money (especially paper money), credit cards, etc.” (WikiDiff)

Forty years ago, when I started wearing suits to work, I carried a wallet in the inside pocket of my suit coat. (The one on the left in the photo below). When I hung up the suits for last time, I switched to a “billfold” (middle) and kept it in a pocket of my laptop case.

Along the way I kept looking for ways to lighten the load and tried some that didn’t fold at all. Just some pocket for credit cards and a magnetic money-clip. I’m giving that a try as I get back in the world.

I’ve long been fascinated by “fat wallets” and collected a few photos over the years. Each of the wallets pictured below were carried in the hip pocket. I would have dearly loved to got through the contents of each of these. What a story they could tell.

And no discussion of wallets would be complete without George Costanza’s exploding wallet. Another scene from the Wallet episode.

Coming Out Day

It’s been two weeks since I received my second dose of COVID-19 vaccine. Time enough for my immune system to generate antibodies to the virus which means exposure to the virus probably won’t put me in the hospital or kill me.

A year ago I was still having lunch with friends in restaurants. And wiping down table tops with antiseptic wipes. (We hadn’t figured out the virus was air-borne.) Soon after Barb and I went into lockdown. We quarantined more diligently than anyone I know and maintained that diligence for a year. When Barb visited her sister they wore masks and did their brief chats outside, twenty feet apart. No birthdays, no Thanksgiving, no Christmas. Serious isolation. You know the drill.

Now that we’ve both been vaccinated, we’re venturing out. Barb going for walks with (vaccinated) friends; sitting in her sister’s (vaccinated) kitchen; going inside the supermarket instead of curbside pickup. We’re still masking in public and will do so until the scientists tell us it’s safe to stop.

Barb and her sister will spend a week at our place in Destin this spring. Just the two of them. They have a lot of catching up to do.

In recent weeks I’ve realized how much the year of near-isolation has affected me. The stress has started to show and I’m eager to get out of the house and be with some friends. “Have you been vaccinated yet?” has become a common refrain. I feel like I’m in a zombie movie. I don’t see any but I know they’re out there. But it’s time to rejoin the living. Wish us luck.